G M2 gangliosidosis - translation to ρωσικά
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G M2 gangliosidosis - translation to ρωσικά

HUMAN DISEASE
GM2 gangliosidosis; Gangliosidoses gm2; Gangliosidosis gm1; GM2 Gangliosidosis; Gangliosidosis (Type2)(GM2); Gm2 gangliosidoses; Gangliosidoses GM2; Gangliosidosis GM1

G M2 gangliosidosis      

медицина

болезнь Тея-Сакса

ганглиозидоз типа II

амавротическая детская ранняя идиотия

g         
  • Pictogram of a Camel
  • Early Etruscan C
  • Early Greek Gamma
  • 10px
  • Typographic variants]] include a double-storey and single-storey '''g'''.
  • 8px
  • Gimel
LETTER OF THE LATIN ALPHABET
G; G (letter); ℊ; Script g; Double-story g; Single-story g; Single-storey g; Openptail g; Looptail g; Double-storey g; Open-tail g; Loop-tail g; ASCII 71; ASCII 103; U+0047; U+0067; Letter G; Opentail g
g I specific gravity noun удельный вес II G - gauss noun гаусс (единица магнитной индукции) III G - giga noun гига- (10 в 9-й степени)
G         
  • Pictogram of a Camel
  • Early Etruscan C
  • Early Greek Gamma
  • 10px
  • Typographic variants]] include a double-storey and single-storey '''g'''.
  • 8px
  • Gimel
LETTER OF THE LATIN ALPHABET
G; G (letter); ℊ; Script g; Double-story g; Single-story g; Single-storey g; Openptail g; Looptail g; Double-storey g; Open-tail g; Loop-tail g; ASCII 71; ASCII 103; U+0047; U+0067; Letter G; Opentail g

[dʒi:]

общая лексика

(giga-) префикс гига-

обозначает 1 миллиард, или 109. В вычислительной технике G означает 230, или 1 073 741 824

сокращение

[gas] газ

газовый

Смотрите также

M; T; generation

существительное

общая лексика

7-я буква английского алфавита

музыка

соль (G)

космонавтика

перегрузка

сленг

тысяча долларов (G.) ([сокр.] от grand)

Смотрите также

G.

Ορισμός

АКСЕЛЕРОМЕТР
(от лат. accelero - ускоряю и ...метр), прибор для измерения ускорений (перегрузок) летательных аппаратов и др.

Βικιπαίδεια

GM2 gangliosidoses

The GM2 gangliosidoses are a group of three related genetic disorders that result from a deficiency of the enzyme beta-hexosaminidase. This enzyme catalyzes the biodegradation of fatty acid derivatives known as gangliosides. The diseases are better known by their individual names: Tay–Sachs disease, AB variant, and Sandhoff disease.

Beta-hexosaminidase is a vital hydrolytic enzyme, found in the lysosomes, that breaks down lipids. When beta-hexosaminidase is no longer functioning properly, the lipids accumulate in the nervous tissue of the brain and cause problems. Gangliosides are made and biodegraded rapidly in early life as the brain develops. Except in some rare, late-onset forms, the GM2 gangliosidoses are fatal.

All three disorders are rare in the general population. Tay–Sachs disease has become famous as a public health model because an enzyme assay test for TSD was discovered and developed in the late 1960s and early 1970s, providing one of the first "mass screening" tools in medical genetics. It became a research and public health model for understanding and preventing all autosomal genetic disorders.

Tay–Sachs disease, AB variant, and Sandhoff disease might easily have been defined together as a single disease, because the three disorders are associated with failure of the same metabolic pathway and have the same outcome. Classification and naming for many genetic disorders reflects history, because most diseases were first observed and classified based on biochemistry and pathophysiology before genetic diagnosis was available. However, the three GM2 gangliosidoses were discovered and named separately. Each represents a distinct molecular point of failure in a subunit that is required for activation of the enzyme.

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